ASH 2023

LYSA studies presented at the 65th ASH congress

The 65th edition of the ASH Annual Meeting and Exhibition takes place from December 9 to 12, 2022 in San Diego, California.

This year, LYSA’s scientific output and studies will be given particular prominence at the meeting, with 27 abstracts in the form of oral communications and posters.

Discover the LYSA presentations!

14 oral communications

  • CD19-Targeting CAR T-Cell Therapy in Transformed Waldenström Macroglobulinemia/Lymphoplasmacytic Lymphoma: A Descar-T and US Collaborative Study

Eric Durot

 

  • Validation of POD24 as a Robust Early Clinical End Point of Poor Survival in Mantle Cell Lymphoma from 1280 Patients on Clinical Trials

Clémentine Sarkozy

 

  • Tazemetostat in Combination with RCHOP in Patients with high-risk, frontline Follicular Lymphoma (Epi-RCHOP): a phase II study from the LYSA

Loic Ysebaert

 

  • Efficacy of Chimeric Antigen Receptor T-Cell Therapy is Not Impaired by Previous Bispecific Antibody Treatment in Patients with Large B-Cell Lymphoma

Gloria Iacoboni

 

  • Real-Word experience of CAR T-cells in Patients with Relapsed/Refractory Follicular Lymphoma : a DESCART Registry Analysis From the LYSA

Loic Ysebaert

 

  • Results of the EpiRCHOP phase II study, evaluating the efficacy of tazemetostat in combination with R-CHOP in elderly newly diagnosed Diffuse Large B Cell Lymphoma (DLBCL): a LYSA Study

Clémentine Sarkozy

 

  • R-GemOx Plus Nivolumab Vs R-GemOx As Second-Line Therapy for Large B-Cell Lymphoma in Transplant-Ineligible Patients: Interim Analysis of the Niveau Trial, an International, Randomized Phase 3 Study of the AGMT, GLA, HOVON, Lysa and PLRG

Gehrard Held

 

  • Single Cell Longitudinal Characterization of FL heterogeneity and residual disease in the Bone Marrow from low-tumor burden FL enrolled in the FLIRT clinical trial

Alicia Beyou

 

  • Combining PET/CT and Ctdna Assessments at 6 Months from Induction Treatment Better Predicts Outcome in Previously Untreated Patients with Follicular Lymphoma: A Relevance Ancillary LYSA Study

Alexis Claudel

 

  • Glofitamab Monotherapy in Patients with Non-Hodgkin B-Cell Lymphoma after Failing CAR T-Cell Infusion: Primary Analysis of the Bicar Study, a Phase II Lysa Study

Pierre Sesques

 

  • Obinutuzumab Versus Rituximab in Transplant Eligible Untreated MCL Patients, a Matching Comparison between the Lyma and Lyma-101 Trials

Clémentine Sarkozy

 

  • Synthetic Control Arm from Clinical Trialsand Real-World Data from Lysa Group forUntreated Diffuse Large B Cell LymphomaPatients Aged over 80 Years: A Bona Fide strategy for Innovative Clinical Trial

Valentin Letailleur

 

  • Induction and Maintenance Therapy in Elderly Patients with Mantle Cell Lymphoma: Double-Randomized MCL R2 Elderly Clinical Trial By the European Mantle Cell Lymphoma Network

Vincent Ribrag

 

  • Genomic, Transcriptional, and Immunological Validation of Distinct Molecular Subtypes of Classic Hodgkin Lymphoma through Tissue-Based and Noninvasive Methods

Stefan K. Alig

13 posters

  • CD20low/CD68high a Promising Microenvironnement Profile Identifying Classical Hos=dgkin Lymphoma Patients with Poor Outcome a LYSA Study

Alexandra Taverse-Glehen

 

  • Very Elderly Rituximab Associated to Lenalidomide – Tafasitamab Combination in Frontline DLBCL Patients”, a Phase II Open-Label Study Evaluating Efficacy of Lenalinomide and Tafasitamab Combination Associated to Rituximab in Frontline Diffuse Large B-Cell Lymphoma Patients of 80 y/o or Older from the Lysa Group

Benoit Tessoulin

 

  • First Line Therapy Evaluation Using Propensity Score Approach in Newly Diagnosed Advanced Classical Hodgkin Lymphoma Patients from Prospective Real-World Realysa Cohort and Phase 3 AHL2011 Trial

Cédric Rossi

 

  • Real World Data of Axicabtagene CiloleucelAs Second Line Therapy for Patients withLarge B Cell Lymphoma: First Results of aLysa Study from the French DESCAR-T registry

Gabriel Brisou

 

  • Marsun, a Phase III, Multicenter, Open Label, Randomized, Controlled Study Investigating Mosunetuzumab-Lenalidomide Versus Investigator Choices in Patients with Relapsed or Refractory Marginal Zone Lymphoma (R/R MZL)

Catherine Thieblemont

 

  • Outcomes of High-Grade B-cell Lymphoma (HGBL-DH, TH, NOS) as compared to other LBCL subtypes in patients treated with CD19-Directed CAR-T cells at 3rd line or more. A LYSA study based on the French DESCAR-T Registry.

Xavier Phina-Ziebin

 

  • Efficacy and Tolerance of Brexucabtagene Autoleucel in Adults with Relapsed/Refractory B-cell Precursor Acute Lymphoblastic Leukemia : A GRAALL study from the DESCAR-T registry

F. Rabian

 

  • Invasive fungal infections after CAR T-cell therapy for B-cell lymphoma: a study from the French DESCART registry

Amélie Bouvier

 

  • French Early Nationwide Idecabtagene Vicleucel (Ide-Cel) Chimeric Antigen Receptor (CAR) T-Cell Therapy Experience in Patients with Relapsed/Refractory Multiple Myeloma (FENIX): Update of the IFM Study from the Descar-T Registry

Sarah Cayla

 

  • Low TMTV InBuences Response and Outcomes in R/R DLBCL 3L+ Patients Treated with CAR-T Cells : First Results of FDG-PET/CT Analysis in the French Descar-T Registry

Yassine Al-Tabaa

 

  • Tislelizumab, an Anti-PD1 Antibody, in Patients with Relapsed/Refractory Classical Hodgkin Lymphoma in Tirhol Bgb-A317-210: A Prospective Multicenter Lysa Phase 2 Study Conducted in Western Countries

Hervé Ghesquieres

 

  • Impact of Brentuximab Vedotin in Patients with Breast Implant–Associated Anaplastic Large Cell Lymphoma with Capsule Infiltration Requiring Chemotherapy

David Sibon

 

  • Distinct Circulating Genomic Features of Classical Hodgkin Lymphoma of Older Adults

Cédric Rossi