Scientific publications on lymphomas

The results and conclusions of the work conducted by the Lymphoma Research Experts ecosystem are published in leading medical journals.

Lysa 2021_LYSA_LRPAP1 autoantibodies in mantle cell lymphoma are associated with superior outcome
Lorenz Thurner, Natalie Fadle, Jörg Thomas Bittenbring, Evi Regitz, Rita Schuck, Onur Cetin, Ariane Stuhr, Torben Rixecker, Niels Murawski, Viola Poeschel, Dominic Kaddu-Mulindwa, Klaus-Dieter Preuss, Stephan Stilgenbauer, Olivier Hermine, Hanneke C. Kluin-Nelemans, Sylvia Hartmann, Martin Dreyling, Christiane Pott, Moritz Bewarder, Eva Hoster
Blood . 2021 Jun 10;137(23):3251-3258. Learn more
Lysa 2021_LYSA_Fusion transcripts FYN-TRAF3IP2 and KHDRBS1-LCK hijack T cell receptor signaling in peripheral T-cell lymphoma, not otherwise specified
Koen Debackere, Lukas Marcelis, Sofie Demeyer, Marlies Vanden Bempt, Nicole Mentens, Olga Gielen, Kris Jacobs, Michael Broux, Gregor Verhoef, Lucienne Michaux, Carlos Graux, Iwona Wlodarska, Philippe Gaulard, Laurence de Leval, Thomas Tousseyn, Jan Cools, Daan Dierickx
Nat Commun . 2021 Jun 17;12(1):3705. Learn more
Lysa 2021_LYSA_A randomized phase 3 trial of autologous vs allogeneic transplantation as part of first-line therapy in poor-risk peripheral T-NHL
Norbert Schmitz , Lorenz Truemper, Krimo Bouabdallah, Marita Ziepert, Mathieu Leclerc, Guillaume Cartron, Arnaud Jaccard, Peter Reimer, Eva Wagner, Martin Wilhelm, Laurence Sanhes, Thierry Lamy, Laurence de Leval, Andreas Rosenwald, Muriel Roussel, Frank Kroschinsky, Walter Lindemann, Peter Dreger, Andreas Viardot, Noel Milpied, Christian Gisselbrecht, Gerald Wulf, Emmanuel Gyan, Philippe Gaulard, Jacques-Olivier Bay, Bertram Glass, Viola Poeschel, Ganhi Damaj, David Sibon, Alain Delmer, Karin Bilger, Anne Banos, Mathias Haenel, Martin Dreyling, Bernd Metzner, Ulrich Keller, Friederike Braulke, Birte Friedrichs, Maike Nickelsen, Bettina Altmann, Olivier Tournilhac
Blood . 2021 May 13;137(19):2646-2656. Learn more
Lysa 2021_LYSA_Risk of relapse after anti-PD1 discontinuation in patients with Hodgkin lymphoma
G Manson, P Brice, C Herbaux, M G Silva, K Bouabdallah, B Deau, J Bouteloup, J M Schiano, E Nicolas-Virelizier, M Maerevoet, H Ghesquieres, A Stamatoullas, C Antier, C Carlo-Stella, M de Charette, F Poizeau, L Dercle, Roch Houot
Eur J Nucl Med Mol Imaging . 2021 May;48(5):1699-1700. Learn more
Lysa 2021_LYSA_Mutational landscape of gray zone lymphoma.
Clementine Sarkozy, Stacy S. Hung, Elizabeth A. Chavez, Gerben Duns, Katsuyoshi Takata, Lauren C. Chong, Tomohiro Aoki, Aixiang Jiang, Tomoko Miyata-Takata, Adele Telenius, Graham W. Slack, Thierry Jo Molina, Susana Ben-Neriah, Pedro Farinha, Peggy Dartigues, Diane Damotte, Anja Mottok, Gilles A. Salles, Rene-Olivier Casasnovas, Kerry J. Savage, Camille Laurent, David W. Scott, Alexandra Traverse-Glehen, Christian Steidl
Blood . 2021 Apr 1;137(13):1765-1776. Learn more
Lysa 2021_LYSA_c-Rel Is the Pivotal NF-κB Subunit in Germinal Center Diffuse Large B-Cell Lymphoma: A LYSA Study
Faumont N, Taoui O, Collares D, Jais J-P, Leroy K, Prévaud L, Jardin F, Molina TJ, Copie-Bergman C, Petit B, Gourin M-P, Bordessoule D, Troutaud D, Baud V, Feuillard J
Front Oncol . 2021 Apr 20;11:638897. Learn more
Lysa 2021_LYSA_Outcomes of older patients with follicular lymphoma using individual data from 5922 patients in 18 randomized controlled trials
Carla Casulo, Jesse G. Dixon, Fang-Shu Ou, Eva Hoster, Bruce A. Peterson, Howard S. Hochster, Pauline Brice, Marco Ladetto, Wolfgang Hiddemann, Robert Marcus, Eva Kimby, Michael Herold, Tina Nielsen, Franck Morschhauser, Mathias Rummel, Anton Hagenbeek, Umberto Vitolo, Gilles A. Salles, Qian Shi, and Christopher R. Flowers, on behalf of the FLASH group
Blood Adv . 2021 Mar 23;5(6):1737-1745. Learn more
Lysa 2021_LYSA_Early progression of disease in follicular lymphoma is a robust correlate but not a surrogate for overall survival
Emmanuel Bachy, James R Cerhan, Gilles Salles
Blood Adv . 2021 Mar 23;5(6):1729-1732. Learn more
Lysa 2021_LYSA_Improving high-resolution copy number variation analysis from next generation sequencing using unique molecular identifiers
Pierre-Julien Viailly, Vincent Sater, Mathieu Viennot, Elodie Bohers, Nicolas Vergne, Caroline Berard, Hélène Dauchel, Thierry Lecroq, Alison Celebi, Philippe Ruminy, Vinciane Marchand, Marie-Delphine Lanic, Sydney Dubois, Dominique Penther, Hervé Tilly, Sylvain Mareschal, Fabrice Jardin
BMC Bioinformatics . 2021 Mar 12;22(1):120. doi: 10.1186/s12859-021-04060-4. Learn more
Lysa 2021_LYSA_Upfront eBEACOPP chemotherapy without consolidation radiotherapy in early-stage unfavourable Hodgkin lymphoma
René-Olivier Casasnovas
Lancet Oncol . 2021 Feb;22(2):161-162. doi: 10.1016/S1470-2045(20)30640-9. Learn more
Lysa 2021_LYSA_EHA/ESMO Clinical Practice Guidelines for the Management of Malignant Lymphoma: Recommendations for the Second Phase of the COVID-19 Pandemic
Martin Dreyling, Igor Aurer, Massimo Federico, Mats Jerkeman, Marie Jose Kersten, Kim Linton, Ulrich Mey, Herve Tilly, Christian Buske
Hemasphere . 2021 Jan 27;5(2):e529. doi: 10.1097/HS9.0000000000000529. Learn more
Lysa 2021_LYSA_The impact of SAMHD1 expression and mutation status in mantle cell lymphoma: An analysis of the MCL Younger and Elderly trial
Tobias Roider,Xi Wang,Katrin Hüttl,Carsten Müller-Tidow,Wolfram Klapper,Andreas Rosenwald,James Peter Stewart,David Gonzalez de Castro,Peter Dreger,Olivier Hermine,Hanneke C. Kluin-Nelemans,Niels Grabe,Martin Dreyling,Christiane Pott,German Ott,Eva Hoster,Sascha Dietrich
Int J Cancer . 2021 Jan 1;148(1):150-160. doi: 10.1002/ijc.33202 Learn more
Lysa 2021_LYSA_Classical Hodgkin lymphoma
Pauline Brice, Eric de Kerviler, Jonathan W Friedberg
Lancet . 2021 Oct 23;398(10310):1518-1527. doi: 10.1016/S0140-6736(20)32207-8. Learn more
Lysa 2021_LYSA_Deep-Learning 18F-FDG Uptake Classification Enables Total Metabolic Tumor Volume Estimation in Diffuse Large B-Cell Lymphoma
Nicolo Capobianco, Michel Meignan, Anne-Segolene Cottereau, Laetitia Vercellino, Ludovic Sibille, Bruce Spottiswoode, Sven Zuehlsdorff, Olivier Casasnovas, Catherine Thieblemont, and Irene Buvat
J Nucl Med . 2021 Jan;62(1):30-36. doi: 10.2967/jnumed.120.242412 Learn more
Lysa 2020_LYSA_Whole genome copy number analysis in search of new prognostic biomarkers in first line treatment of mantle cell lymphoma. A study by the LYSA group
Yannick Le Bris, Florence Magrangeas, Anne Moreau, David Chiron, Catherine Guérin-Charbonnel, Olivier Theisen, Olivier Pichon, Danielle Canioni, Barbara Burroni, Hervé Maisonneuve, Catherine Thieblemont, Lucie Oberic, Emmanuel Gyan, Catherine Pellat-Deceunynck, Olivier Hermine, Marie-Hélène Delfau-Larue, Benoît Tessoulin, Marie-Christine Béné, Stéphane Minvielle, Steven Le Gouill
Hematol Oncol . 2020 Oct;38(4):446-455. doi: 10.1002/hon.2750. Learn more
Lysa 2020_LYSA_Safety and efficacy of temsirolimus in combination with three different immuno-chemotherapy regimens in relapse and refractory mantle cell lymphoma, final results of the T 3 phase IB trial of the LYSA
Benoît Tessoulin, Kamal Bouabdallah, Barbara Burroni, Thierry Lamy, Remy Gressin, Guillaume Cartron, Catherine Thieblemont, Clémentine Sarkozy, Corinne Haioun, Olivier Casasnovas, Clementine Joubert, Emmanuel Gyan, Olivier Hermine, Steven Le Gouill
Ann Hematol . 2020 Aug;99(8):1771-1778. doi: 10.1007/s00277-020-04159-3. Learn more
Lysa 2020_LYSA_Lenalidomide/rituximab induces high molecular response in untreated follicular lymphoma: LYSA ancillary RELEVANCE study
Marie-Helene Delfau-Larue, Marie-Laure Boulland, Asma Beldi-Ferchiou, Pierre Feugier, Hervé Maisonneuve, Rene-Olivier Casasnovas, François Lemonnier, Gian Matteo Pica, Roch Houot, Loic Ysebaert, Hervé Tilly, Jean-Claude Eisenmann, Steven Le Gouill, Vincent Ribrag, Pascal Godmer, Sylvie Glaisner, Guillaume Cartron, Luc Xerri, Gilles André Salles, Thierry Fest, Franck Morschhauser
Blood Adv . 2020 Aug 11;4(14):3217-3223. doi: 10.1182/bloodadvances.2020001955. Learn more
Lysa 2020_LYSA_Fully automatic segmentation of diffuse large B cell lymphoma lesions on 3D FDG-PET/CT for total metabolic tumour volume prediction using a convolutional neural network
Paul Blanc-Durand, Simon Jégou, Salim Kanoun, Alina Berriolo-Riedinger, Caroline Bodet-Milin, Françoise Kraeber-Bodéré, Thomas Carlier, Steven Le Gouill, René-Olivier Casasnovas, Michel Meignan, Emmanuel Itti
Eur J Nucl Med Mol Imaging . 2020 Oct 24. doi: 10.1007/s00259-020-05080-7 Learn more
Lysa 2020_LYSA_Molecular response after obinutuzumab plus high-dose cytarabine induction for transplant-eligible patients with untreated mantle cell lymphoma (LyMa-101): a phase 2 trial of the LYSA group
Steven Le Gouill, Asma Beldi-Ferchiou, Marion Alcantara, Victoria Cacheux, Violaine Safar, Barbara Burroni, Stéphanie Guidez, Thomas Gastinne, Danielle Canioni, Catherine Thieblemont, Hervé Maisonneuve, Caroline Bodet-Milin, Roch Houot, Lucie Oberic, Krimo Bouabdallah, Charles Bescond, Ghandi Damaj, Arnaud Jaccard, Nicolas Daguindau, Anne Moreau, Hervé Tilly, Vincent Ribrag, Marie-Hélène Delfau-Larue, Olivier Hermine, Elizabeth Macintyre
https://doi.org/10.1016/S2352-3026(20)30291-X Learn more
Lysa 2020_LYSA_Tazemetostat for patients with relapsed or refractory follicular lymphoma: an open-label, single-arm, multicentre, phase 2 trial
Franck Morschhauser, Hervé Tilly, Aristeidis Chaidos, Pamela McKay, Tycel Phillips, De Sarit Assouline, Connie LeeBatlevi, Phillip Campbell, Vincent Ribrag, Gandhi Laurent Damaj, Michael Dickinson, Wojciech Jurczak, Maciej Kazmierczak, Stephen Opat, John Radford, Anna Schmitt, Jay Yang, Jennifer Whalen, Gilles Salles
https://doi.org/10.1016/S1470-2045(20)30441-1 Learn more
Lysa 2020_LYSA_Obinutuzumab versus Rituximab in young patients with advanced DLBCL, a PET-guided and randomized phase 3 study by LYSA
Steven Le Gouill, Herve Ghesquieres, Lucie Obéric, Franck Morschhauser, Herve Tilly, Vincent Ribrag, Thierry Lamy, Catherine Thieblemont, Herve Gerard Maisonneuve, Remy Gressin, Krimo Bouabdallah, Corinne Haioun, Gandhi Damaj, Luc-Matthieu Fornecker, Reda Bouabdallah, Pierre Feugier, David Sibon, Guillaume Cartron, Christophe Bonnet, Marc André, Loic Chartier, Philippe Ruminy, F Kraeber-Bodere, C Bodet-Milin, Alina Berriolo-Riedinger, Josette Briere, Jean-Philippe Jais, Thierry Molina, Emmanuel Itti, Olivier Casasnovas
Blood. 2020 Nov 19;blood.2020008750. doi: 10.1182/blood.2020008750 Learn more
Lysa 2020_LYSA_Risk stratification in diffuse large B cell lymphoma using lesion dissemination and metabolic tumor burden calculated from baseline PET/CT
A S Cottereau, M Meignan, C Nioche, N Capobianco, J Clerc, L Chartier, L Vercellino, O Casasnovas, C Thieblemont, I Buvat
Ann Oncol . 2020 Dec 2;S0923-7534(20)43174-6. doi: 10.1016/j.annonc.2020.11.019. Learn more
Lysa 2020_LYSA_Predictive factors of early progression after CAR T-cell therapy in relapsed/refractory diffuse large B-cell lymphoma
Laetitia Vercellino, Roberta Di Blasi, Salim Kanoun, Benoit Tessoulin, Cedric Rossi, Maud D'Aveni-Piney, Lucie Obéric, Caroline Bodet-Milin, Pierre Bories, Pierre Olivier, Ingrid Lafon, Alina Berriolo-Riedinger, Eugenio Galli, Sophie Bernard, Marie-Thérèse Rubio, Celine Bossard, Veronique Meignin, Pascal Merlet, Pierre Feugier, Steven Le Gouill, Loic Ysebaert, Olivier Casasnovas, Michel Meignan, Sylvie Chevret, Catherine Thieblemont
Blood Adv . 2020 Nov 24;4(22):5607-5615. doi: 10.1182/bloodadvances.2020003001. Learn more
Calym 2017_RECQ1 helicase is involved in replication stress survival and drug resistance in multiple myeloma.
Viziteu E, Klein B, Basbous J, Lin YL, Hirtz C, Gourzones C, Tiers L, Bruyer A, Vincent L, Grandmougin C, Seckinger A, Goldschmidt H, Constantinou A, Pasero P, Hose D and Moreaux J
2017. Jun 2;45(10):5639-5652. Learn more